زیست فناوری میکروبی و مهندسی زیستی

زیست فناوری میکروبی و مهندسی زیستی

مروری بر استخراج روغن تک‌یاخته از سویه میکروبی Candida Utilis

نوع مقاله : مروری

نویسنده
کارشناسی ارشد، مهندسی شیمی-بیوتکنولوژی، دانشگاه شهید باهنر کرمان
چکیده
اسیدهای چرب ضروری، به‌عنوان یکی از اجزای حیاتی رژیم غذایی، نقش مهمی در عملکرد بدن ایفا می‌کنند. از آنجا که بدن انسان قادر به سنتز این اسیدهای چرب غیراشباع (دارای چندین پیوند دوگانه) نیست، دریافت آن‌ها از طریق منابع غذایی ضروری است. اهمیت تغذیه‌ای روغن‌های تک‌یاخته تولیدشده توسط مخمرها، به دلیل غنای آن‌ها در اسیدهای چرب غیراشباع با زنجیره بلند است. این ویژگی منحصر‌به‌فرد، منجر به استفاده گسترده از میکروارگانیسم‌های لیپیدساز در صنایع تولید مکمل‌های غذایی و روغن‌های تک‌یاخته شده است. اخیراً، میکروارگانیسم‌های مولد روغن به‌عنوان منبعی پایدار و جایگزین برای تولید اسیدهای چرب غیراشباع مورد توجه ویژه قرار گرفته‌اند. ویژگی‌هایی نظیر نرخ رشد بالا و توانایی متابولیسم طیف وسیعی از منابع کربن، این میکروارگانیسم‌ها را به گزینه‌ای جذاب برای تولید صنعتی روغن‌های تک‌یاخته تبدیل کرده است. لیپیدهای سنتز‌شده توسط این موجودات، کاربردهای گسترده‌ای در صنایع غذایی و دارویی دارند. علاوه بر این، نوع منبع کربن نقش تعیین‌کننده‌ای در فرآیند تجمع لیپید ایفا می‌کند. در همین راستا، مطالعات متعددی در سطح جهانی و توسط محققان بر روی مخمرهای لیپیدساز، شرایط بهینه تولید و پارامترهای مؤثر بر میزان بیوسنتز لیپید انجام پذیرفته است تا بازده و کیفیت این محصولات بهینه‌سازی شود.
کلیدواژه‌ها

عنوان مقاله English

A Review on the Extraction of Single Cell Oil from the Microbial Strain Candida utilis

نویسنده English

Atefeh Farjadmanesh
M.Sc., Chemical Engineering – Biotechnology, Shahid Bahonar University of Kerman, Iran
چکیده English

Essential fatty acids, as vital components of the diet, play a crucial role in human physiological functions. Since the human body cannot synthesize these unsaturated fatty acids (characterized by multiple double bonds), they must be obtained through dietary sources. The nutritional significance of single-cell oils (SCO) produced by yeasts lies in their richness in long-chain unsaturated fatty acids. This unique feature has led to the widespread utilization of lipid-producing microorganisms in the manufacturing of dietary supplements and SCOs. Recently, oil-producing microorganisms have gained significant attention as a sustainable and alternative source for unsaturated fatty acid production. Attributes such as high growth rates and the ability to metabolize a wide range of carbon sources make these microorganisms an attractive option for the industrial production of SCOs. The lipids synthesized by these organisms find extensive applications in the food and pharmaceutical industries. Furthermore, the type of carbon source plays a decisive role in the lipid accumulation process. In this context, numerous studies conducted by researchers worldwide have focused on lipid-producing yeasts, optimal production conditions, and parameters affecting lipid biosynthesis, aiming to optimize the yield and quality of these products.

کلیدواژه‌ها English

Biotechnology
Microbial production of organic acids
Agricultural waste
Single cell oil
Candida utilis
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دوره 1، شماره 1
اردیبهشت 1405
صفحه 59-46

  • تاریخ دریافت 27 اردیبهشت 1405
  • تاریخ بازنگری 10 خرداد 1405
  • تاریخ پذیرش 26 خرداد 1405
  • تاریخ اولین انتشار 26 خرداد 1405